ZincNutrition library
Zinc
A cofactor for hundreds of enzymes involved in DNA synthesis, cell division and immune function — critical during the fastest-growth periods.
How this interacts
Meal-resolved zinc
Per meal: zinc and phytate are converted to a molar ratio (mg ÷ molecular weight). Absorption fraction follows the IZiNCG/WHO bioavailability bands — ~50% when phytate:zinc is low, tapering to ~15% when it's high — smoothly interpolated between those bands rather than stepping abruptly. Summed to a day total and compared against an absorbed-zinc target (the gross RDA × the ~27% absorption fraction the RDA itself already assumes for a moderate-phytate diet).
Phytate vs. minerals
Phytic acid (IP6), concentrated in the bran/germ of grains, legumes and nuts, chelates zinc, iron and (more mildly) magnesium in the gut, blocking some of their absorption. The effect is dose-dependent: more phytate relative to the mineral means a larger blocked fraction. Vitamin C specifically counteracts phytate's effect on iron (not zinc) by forming an absorbable iron-ascorbate complex.
Tracked by these blood markers
- Serum zincµmol/L
Trimester focus
| Stage | For the mother | For the baby |
|---|---|---|
| First trimester | Supports the immune adaptations of early pregnancy. | Essential for DNA synthesis during the most rapid cell-division period. |
| Second trimester | Continues supporting maternal immune and tissue-repair function. | Supports organ growth and ongoing cell division. |
| Third trimester | Stays important for tissue growth and immune function. | Supports continued growth and the developing immune system. |
Connections
See also
- Serum zincmarker
- Ironcofactor
- Magnesiumcofactor
- Ironrelated
- Magnesiumrelated
Evidence & sources
- Evidence-backed[1] Zinc absorption falls as phytate:zinc molar ratio risesIZiNCG/WHO bioavailability classes by phytate:zinc molar ratio: <5 ~50% absorption ("high"), 5-15 ~30% ("moderate"), >15 ~15% ("low") — formalised in a mathematical model of zinc absorption vs dietary zinc and phytate.
- Evidence-backed[2] Absorbed-zinc target derives from the dietary RDA's own assumptionThe IOM zinc RDA is itself a factorial estimate (physiological requirement ÷ an assumed absorption fraction for a moderate-bioavailability mixed diet, ~27%) — this engine's absorbed-zinc target is that same fraction of whichever gross target applies for the phase, so it automatically tracks any future correction to the gross target.
References
- Hotz C, Brown KH (eds, for IZiNCG). International Zinc Nutrition Consultative Group (IZiNCG) technical document #1. Assessment of the risk of zinc deficiency in populations and options for its control. Food Nutr Bull 2004PMID 18046856
- Miller LV, Krebs NF, Hambidge KM. A mathematical model of zinc absorption in humans as a function of dietary zinc and phytate. J Nutr 2007PMID 17182814
Target note
Oyster-driven; watch the 40 mg UL. The Assessment tab scores modelled ABSORBED zinc (phytate-limited per meal, like iron) against an absorbed target, alongside the separate gross 40 mg UL check.